The future of red cell alloimmunization

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Responder individuality in red blood cell alloimmunization.

Many different factors influence the propensity of transfusion recipients and pregnant women to form red blood cell alloantibodies (RBCA). RBCA may cause hemolytic transfusion reactions, hemolytic disease of the fetus and newborn and may be a complication in transplantation medicine. Antigenic differences between responder and foreign erythrocytes may lead to such an immune answer, in part with...

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Red cell alloimmunization in repeatedly transfused patients

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Frequency and Risk Factors of Red Blood Cell Alloimmunization in Thalassemia Major Patients in Markazi province

Background: Thalassemia is one of the most common genetic disorders throughout the world. Blood transfusion plays an important role in the treatment of thalassemia but it leads to numerous complications such as iron overload and alloimmunization. This study evaluated the frequency and risk factors associated with alloimmunization in thalassemia major patients living in Markazi province, Iran. ...

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Red-blood-cell alloimmunization and number of red-blood-cell transfusions.

BACKGROUND Patients receiving red-blood-cells may form antibodies against the alloantigens expressed by red-blood-cells, with the risk of serious morbidity and the need for extensive phenotype-matching in subsequent transfusions. The incidence of alloimmunization is considered variable for specific patient groups and for first time antibody formation. We therefore studied the cumulative inciden...

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Benefits of Delayed Cord Clamping in Red Blood Cell Alloimmunization.

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ژورنال

عنوان ژورنال: Transfusion

سال: 2007

ISSN: 0041-1132,1537-2995

DOI: 10.1111/j.1537-2995.2007.01495.x